Archive for the ‘Stroke’ Category

Resveratrol Reduces High Blood Pressure Caused by Estrogen Exposure

Saturday, May 28th, 2011
Researchers at Michigan State University recently published a study in the American Journal of Physiology – Regulatory, Integrative, and Comparative Physiology that revealed resveratrol reverses increases in blood pressure due to chronic estrogen exposure. Many women take estrogen as a means to combat menopause (known as hormone replacement therapy – HRT).  Estrogen is also found in small amounts in birth control pills.
In the study, the researchers injected mice with estrogen. The researchers noticed that the estrogen significantly increased the animals’ blood pressures – most likely through the buildup of superoxide in the brain. The researcher then fed resveratrol to the mice and their blood pressures (and superoxide levels) returned to their levels before the estrogen injections. 
High blood pressure, also known as hypertension, is a contributing factor to numerous health problems including heart attack, congestive heart failure, stroke, poor or lost vision, brain damage, and kidney disease. 

Resveratrol Fights the Ill Effects of Dietary Salt

Thursday, September 30th, 2010
Australian researchers have determined that resveratrol can fight against the ill effects of a diet too high in sodium. In the study, salt was added to the drinking water of mice for 28 days. One group of the mice received an oral resveratrol  dose (1 mg/kg/day) and another ‘control’ group did not. 
The group of mice that did receive resveratrol experienced decreased inflammation, decreased abnormal thickening of heart valves, and improved cardiac and vascular function. The group not receiving resveratrol did not experience these benefits.
Editor’s Note: the equivalent dose of resveratrol for a 150 pound human (all things being equal) would be 68 mg. per day. This dose is easily achievable in one supplement pill per day. 

Resveratrol Protects Brain From Stroke

Wednesday, May 19th, 2010

In a recent study conducted at John’s Hopkins, researchers discovered that resveratrol protects the brain from stroke damage.  Specifically, researchers fed one group of mice a ‘modest’ amount of resveratrol (while not feeding a second group resveratrol).   The researchers then cut off blood supply to the brains of both groups of mice – thereby inducing stroke.  

The mice that were fed resveratrol suffered significantly less brain damage than the mice not fed resveratrol.  In effect, resveratrol ‘went beyond’ its typical antioxidant role; that is, not only did resveratrol itself protect brain cells from damage, but it also signaled the brain cells to protect themselves from damage.  Might resveratrol be used to protect humans from stroke damage in the near future?


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